Predicting stabilizing mutations in proteins using Poisson-Boltzmann based models: study of unfolded state ensemble models and development of a successful binary classifier based on residue interaction energies

Phys. Chem. Chem. Phys., 2015, Accepted Manuscript
DOI: 10.1039/C5CP04348D, Paper

Jorge Estrada, Pablo Echenique, Javier Sancho
In many cases the stability of a protein has to be increased to permit its biotecnological use. Rational methods of protein stabilization based on optimizing electrostatic interactions have provided some...
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