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Aggregation of [small alpha]-crystallins in kynurenic acid-sensitized UVA photolysis under anaerobic conditions

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Phys. Chem. Chem. Phys., 2016, Advance Article
DOI: 10.1039/C5CP06693J, Paper
P. S. Sherin, E. A. Zelentsova, E. D. Sormacheva, V. V. Yanshole, T. G. Duzhak, Yu. P. Tsentalovich
Extensive protein aggregation is the major outcome of kynurenic acid-sensitized photolysis of [small alpha]-crystallin under anaerobic conditions. The main lens antioxidants ascorbate and glutathione effectively inhibit the protein aggregation.
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